PacBio was founded in 2004 to develop sequencing methods based on work done in the labs of biophysicist Watt Webb and engineer Harold Craighead, both at Cornell University. The previous year, the two had collaborated to create zero-mode waveguides (ZMWs): small containers just big enough to hold a single DNA polymerase and containing tiny holes at the bottom through which light could be detected. They were able to fix a DNA polymerase to the bottom of a ZMW and detect the incorporation of individual fluorescent “C” nucleotides through the holes, which fed into a microscope capable of detecting light emissions.
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Hotel owners, councillors and residents have objected to the plans and warned they could increase disturbance.
消费者和投资人都希望西贝“变”，甚至“巨变”。
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Per-script breakdown
Apple packaged in some sample HyperCard stacks to get people up to speed with the software, including one called "Art Bits", which included a ton of sample clip art for use in your own stacks. This stack is fantastic for showing off just how much Apple could do with two colors.，详情可参考PDF资料