Patients regain weight rapidly after stopping weight loss drugs – but still keep off a quarter of weight lost. A year after stopping taking weight loss drugs such as Ozempic and Wegovy, people regain on average 60% of their lost weight and manage to keep off 25% of the weight lost to treatment.

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"But you must keep up the exercise regime. Because you're staying fit in space, not for space itself, but for when you return back to the punishing gravity environment of Earth. Those first two or three days back on Earth can be really punishing."

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